|Protein Crystallography Research Group (Dubin Lab)|
Research grants and other funding: (follow the links below for details)
2021-2025 National Centre of Science, Poland Structural insight into the peroxisomal protein import - the PEX translocon
2019-2023 National Agency for Scientific Exchange, Poland Novel approaches for diabetes management by combination of inhibition of DYRK1A kinase and stem cells application
2018-2021 National Centre of Science, Poland Characterization of Trypanosoma cruzi PEX5 as a promising target in Chagas disease.
2018-2020 National Centre of Science, Poland Structural and functional analysis of immune checkpoints.
2014-2018 National Centre of Science, Poland Intermediate protein states in the design of low molecular weight inhibitors of protein-protein interaction.
2013-2017 National Centre of Science, Poland Extracellular proteolytic activity of human epithelium - role in modulation of signal transduction.
2013-2016 National Centre of Science, Poland New kinases of important role in cancer - structural characterization.
2011-2015 National Centre of Science, Poland Structural studies on proteases of unknown catalytic mechanism. Development of unique team of researchers focused on structural studies at the Jagiellonian University and at the Malopolska Centre of Biotechnology
2011-2012 Ministry of Science and Higher Education, Poland Structural characterization of a novel bacterial protease
2012 Biotechnology company Characterization of biosimilars
2010-2013 National Centre of Research and Development, Poland Anticancer therapy of the future – a search for low-molecular-weight activators of p53 pathway
2000s Pharmaceutical company A drug discovery project
2008-2010 Ministry of Science and Higher Education, Poland Towards a consistent picture of extracellular proteolytic activity of Staphylococcus aureus – characterization of the role of Spl proteases and epidermolytic toxins.
2007-2014 European Union and Polish Government Malopolskie Center for Biotechnology (MCB) (subtask – X-ray Crystallography Laboratory)
2007-2009 National Centre of Research and Development, Poland Technical Initiative I – Expression platform for recombinant proteins in the Gram positive bacteria.
2007 Foundation for Polish Science, Poland Expansion of scientific potential of the Protein Crystallization Laboratory at the Faculty of Biochemistry, Biophysics and Biotechnology of the Jagiellonian University
2005-2007 Ministry of Science and Higher Education, Poland Characterization of Spl proteases of Staphylococcus aureus.
2006 European Social Fund and Polish Government Characterization of Staphylococcal Spl proteases. Protein Crystallization Laboratory.
2002-2005 European Commission (Archimedes Prize 2002) Natural, specific inhibitors of Staphylococcal proteases – new treatments for bacterial infections.